| 发明名称 |
PROCESS FOR THE PREPARATION OF 3-HALOALKYLPYRAZOLES |
| 摘要 |
The present invention provides a process for the preparation of a compound of formula I:;;wherein R1 is C1-C4 haloalkyl;
R2 is optionally substituted alkyl, optionally substituted aryl or optionally substituted heteroaryl; andR3 is methyl or ethyl;
comprising reacting a compound of formula IV:
;;wherein R1, R2 and R3 are as defined for the compound of formula I;
with an alkylating agent in the presence of an amide. |
| 申请公布号 |
US2016244413(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201615145232 |
申请日期 |
2016.05.03 |
| 申请人 |
Syngenta Participations AG |
发明人 |
WANG Linhua;SHETH Ritesh Bharat |
| 分类号 |
C07D231/14 |
主分类号 |
C07D231/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for the preparation of a compound of formula I: wherein R1 is C1-C4 haloalkyl; R2 is optionally substituted alkyl, optionally substituted aryl or optionally substituted heteroaryl; and R3 is methyl or ethyl; comprising b1. reacting a compound of formula II: wherein R1 and R2 are as defined for the compound of formula I; with an alkylating agent to produce a mixture comprising a compound of formula I and a compound of formula IV wherein R1, R2 and R3 are as defined for the compound of formula I; and b2. reacting the mixture from b1. with an alkylating agent in the presence of an amide. |
| 地址 |
Basel CH |
