| 摘要 |
Methods for determining a predisposition to and presence of an inflammatory disease, disorder or condition in a subject, which include evaluating the expression level of PAG1 in a biological sample from the subject, are provided. Also provided is a method for preventing or treating an inflammatory disease, disorder or condition in a subject, including administration of an agent that inhibits or prevents expression and/or activity of of PAG1 to said subject. A method for identifying, designing and/or engineering an agent for the inhibition of PAG1, as well as the agent identified, designed and/or engineered therefrom, is further provided. |
