发明名称 |
ANTIBODIES DIRECTED AGAINST INTERLEUKIN 36 RECEPTOR (IL-36R) |
摘要 |
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R). The invention provides an IL-36R-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-36R-binding agent to treat a disorder or disease that is responsive to IL-36R inhibition, such as cancer, an infectious disease, or an autoimmune disease. |
申请公布号 |
WO2016168542(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
WO2016US27676 |
申请日期 |
2016.04.15 |
申请人 |
ANAPTYSBIO, INC. |
发明人 |
BOWERS, Peter;MCKNIGHT, Andrew John;KING, David J.;LONDEI, Marco |
分类号 |
A61K39/395;A61P9/10;A61P29/00;A61P37/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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