USE OF SOLUBLE CD146 AS A BIOMARKER TO SELECT IN VITRO-FERTILIZED EMBRYO FOR IMPLANTATION IN A MAMMAL

摘要

The present invention relates to the field of human fertility treatment. The present invention more specifically relates to the identification of soluble CD 146 (sCD146) as a biomarker which, when measured in an embryo culture medium, can be used to determine whether the embryo can be selected for implantation in the uterus of a mammal or not. The present invention thus provides a new tool and related kits to (pre)select embryo eligible for implantation. The invention also relates to methods for promoting pregnancy in a human who undergoes embryo transfer.