| 发明名称 |
Etanercept Formulations Stabilized with Xylitol |
| 摘要 |
The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same. |
| 申请公布号 |
US2016317667(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201615209484 |
申请日期 |
2016.07.13 |
| 申请人 |
Coherus Biosciences, Inc. |
发明人 |
Manning Mark;Murphy Brian |
| 分类号 |
A61K47/26;C07K14/715;A61K47/18 |
主分类号 |
A61K47/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stabilized aqueous pharmaceutical composition comprising etanercept and a stabilizer to inhibit instability, misfolding aggregation and/or fragmentation of the etanercept, wherein the stabilizer comprises xylitol and meglumine, and wherein the composition is free or essentially free of arginine. |
| 地址 |
Redwood City CA US |
