Fluorescent Polymer Dots, Methods For Their Preparation, And Uses Thereof

摘要

There is provided a fluorescent polymer dot (FPdot) comprising one or more fluorescent conjugated polymers forming a hydrophobic core and one or more amphiphilic molecules, each amphiphilic molecule comprising a hydrophobic end embedded in the core and a hydrophilic end that forms a hydrophilic shell surrounding the core, wherein said hydrophobic end comprises one or more aliphatic chain moieties. There is also provided a method for preparing the fluorescent polymer dot comprising preparing a mixture of conjugated polymer and amphiphilic molecule in an aprotic solvent; and adding said mixture to a protic solvent. The fluorescent polymer dots may be useful in biomedical imaging applications.

主权项

1. A fluorescent polymer dot comprising one or more fluorescent conjugated polymers, forming a hydrophobic core and one or more amphiphilic molecules, each amphiphilic molecule comprising a hydrophobic end embedded in the core and a hydrophilic end that forms a hydrophilic shell surrounding the core, wherein said hydrophobic end comprises one or more aliphatic chain moieties.