Methods for isolating a target analyte from a heterogeneous sample

摘要

The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.

主权项

1. A method for isolating pathogens from a heterogeneous sample, the method comprising
obtaining a heterogeneous sample comprising pathogens; introducing the heterogeneous sample into a fluidic device through a vessel interface of the fluidic device; introducing to the heterogeneous sample from a reagent storage chamber of the fluidic device a composition comprising at least one magnetic particle conjugated to at least two sets of capture moieties, wherein each set of capture moieties is specific for different pathogen, incubating in the fluidic device the sample and the composition; and identifying the different pathogens in the sample.