DIAGNOSTIC MEANS USEFUL FOR PREDICTIVE ASSESSMENT OF HUMAN HEPATOCELLULAR CARCINOMA DISEASE (HCC), AS WELL AS DIAGNOSTIC METHODS USING THE SAME

摘要

The present invention pertains to new polynucleotides or new combinations of polynucleotides useful as diagnostic tools for predicting the occurrence of a human hepatocellular carcinoma disease. The invention is also directed to polynucleotides that consist in candidate tumor suppressor genes the alteration of which is involved in the occurrence of hepatocellular carcinoma in a patient, as well as to polynucleotides derived from such new candidate tumor suppressor genes and to the corresponding expressed polypeptides. The invention also concerns diagnostic methods using said polynucleotides as diagnostic tools.