发明名称 NOVEL LACTAMS AND USES THEREOF
摘要 <p>This invention relates to novel compounds having formula (I) to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit secretase and thereby inhibit the production of amyloid ß protein, thereby acting to prevent the formation of neurological deposits of amyloid protein. The present invention relates to the treatment of neurological disorders related to amyloid ß - protein production such as Alzheimer's disease.</p>
申请公布号 WO2004080983(A1) 申请公布日期 2004.09.23
申请号 WO2004SE00350 申请日期 2004.03.10
申请人 ASTRAZENECA AB;HERZOG, KEITH, JOHN;JACOBS, ROBERT;KANG, JIANXING;SIMPSON, THOMAS, RICHARD;WOODS, JAMES, M. 发明人 HERZOG, KEITH, JOHN;JACOBS, ROBERT;KANG, JIANXING;SIMPSON, THOMAS, RICHARD;WOODS, JAMES, M.
分类号 A61P25/28;C07D223/12;C07D409/12;C07K5/06;(IPC1-7):C07D243/24;A61K31/55;C04D223/16 主分类号 A61P25/28
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