发明名称 |
THERAPEUTIC OR PROPHYLACTIC AGENT, DETECTION METHOD AND DETECTION AGENT FOR METABOLIC SYNDROME, AND METHOD FOR SCREENING OF CANDIDATE COMPOUND FOR THERAPEUTIC AGENT FOR METABOLIC SYNDROME |
摘要 |
The object is to provide: a therapeutic or prophylactic agent for metabolic syndrome, which has improved stability in a living body; and others. The therapeutic or prophylactic agent for metabolic syndrome comprises, as an active ingredient, DNA that encodes receptor activity-modifying protein (RAMP) 2 and is selected from the items (a) to (d) below or a polypeptide encoded by the DNA: (a) DNA which has the nucleotide sequence depicted in SEQ ID NO:1; (b) DNA which has a nucleotide sequence capable of hybridizing with the nucleotide sequence depicted in SEQ ID NO:1 under stringent conditions; (c) DNA which has a nucleotide sequence encoding an amino acid sequence having the substitution, deletion and/or addition of one or more amino acid residues in the amino acid sequence depicted in SEQ ID NO:2; and (d) DNA which has a nucleotide sequence having a 90% or more homology with the nucleotide sequence depicted in SEQ ID NO:1. |
申请公布号 |
EP2221065(B1) |
申请公布日期 |
2016.12.28 |
申请号 |
EP20080855467 |
申请日期 |
2008.11.21 |
申请人 |
Japan Science and Technology Agency |
发明人 |
SHINDO, Takayuki |
分类号 |
A61K48/00;A61K38/00;A61P1/00;A61P3/00;A61P3/04;A61P3/08;A61P3/10;A61P9/00;A61P9/10;A61P9/12;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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