发明名称 |
GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTOR & ITS NUCLEIC ACID AND AMINO ACID SEQUENCES |
摘要 |
PURPOSE: A receptor for Glial cell line-Derived Neurotrophic Factor(GDNFR) and nucleic acid and amino acid sequences for GDNFR protein products are described. Also provided is treating method for GDNF-response syndrome. CONSTITUTION: The GDNFR protein products are produced by recombination of genetic engineering. The process comprises the steps of: Culturing of host cell which comprises GDNFR; Preserving the host cell at proper condition; Separating GDNFR protein products selectively from the host cell. In case of GDNF-related syndrome, a treating method increases sensitivity to GDNF or intercepts GDNF- activity.
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申请公布号 |
KR20000010571(A) |
申请公布日期 |
2000.02.15 |
申请号 |
KR19987008430 |
申请日期 |
1998.10.21 |
申请人 |
AMGEN INC. |
发明人 |
FOX GARY M.;WEN DUANZHI;JING SHUQIAN |
分类号 |
C12N15/09;A61K9/48;A61K31/00;A61K38/00;A61K38/17;A61K39/395;A61P25/16;A61P25/28;C07K14/705;C07K14/71;C07K16/28;C12N1/21;C12N5/10;C12N15/12;C12P21/02;C12P21/08;G01N33/53;G01N33/566;G01N33/68;(IPC1-7):C12N15/12 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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