| 发明名称 |
USE OF IMIDAZOLYL CYCLIC ACETAL DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DISEASES MEDIATED BY THE ALK5 RECEPTORS |
| 摘要 |
The use of imidazolyl-cyclic acetals as inhibitors of the tranforming growth factor, ("TGF")- beta beta signaling pathway, in particular, the phosphorylation of smad2 or smad3 bz the type I or activinlike kinase (ALK")-5 receptor are disclosed.
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| 申请公布号 |
WO02055077(A1) |
申请公布日期 |
2002.07.18 |
| 申请号 |
WO2002EP00112 |
申请日期 |
2002.01.07 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;GASTER, LARAMIE, MARY |
发明人 |
GASTER, LARAMIE, MARY |
| 分类号 |
A61K31/00;A61K31/498;A61K31/5377;A61P1/04;A61P3/10;A61P9/10;A61P11/00;A61P13/12;A61P19/02;A61P19/10;A61P25/28;A61P27/02;(IPC1-7):A61K31/417;A61K31/44;A61K31/442;A61K31/443;A61K31/444;A61K31/496;A61K31/505;A61K31/506;A61K31/537;A61K31/541 |
主分类号 |
A61K31/00 |
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