| 摘要 |
<p>The invention disclosed herein relates to an implanted medical device for detection and treatment of syncope by a detector (28), comprising an algorithm for determining the presence of syncope based on physiological activity associated with the onset of a syncopal episode, and a means for infusing a drug (24, 28). Drug infusion therapy may be used along or in combination with pacing via a pacing pulse generator (38). The physiological activities detected by a sense amp (36) and used by the device are selected from the group including changes in heart rate, heart rate variability, QT interval, PR interval, pressure, blood flow, vagal nerve activity, temperature, pH, and AV conduction times, respiration rate, position, motion, and combinations thereof. Drugs which may be used with the invention include pharmaceutical compositions which are capable of both endocardial administration and treatment of syncope, such as composition comprising beta blockers.</p> |
