发明名称 |
Process for producing phospholipid-containing drugs |
摘要 |
The present invention provides a pharmaceutical preparation which is safe, little irritate subjects and comprises a water-insoluble or hardly water-soluble drug at a high level, and a simple and convenient process for producing the preparation. A process for producing a pharmaceutical composition comprising a water-insoluble or hardly water-soluble drug coated with phospholipid, said process comprising mixing a solution containing the water-insoluble or hardly water-soluble drug and phospholipid in an organic solvent with an aqueous solvent, emulsifying the resultant mixture and removing the organic solvent from the emulsion thus obtained to form a phospholipid coating film on the surface of the water-insoluble or hardly water-soluble drug. |
申请公布号 |
AU7458601(A) |
申请公布日期 |
2002.01.02 |
申请号 |
AU20010074586 |
申请日期 |
2001.06.22 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES LTD. |
发明人 |
TETSUO HOSHINO;KAZUHIRO SAITO |
分类号 |
A61K9/16;A61K9/50;A61K31/67;C07F9/6561 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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