| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a means enabling a thrombotic disease to be diagnosed at an early stage and the morbid risk thereof to be judged. <P>SOLUTION: The method for detecting the gene having possibility of causing the coronary artery disease comprises means identifying that the haplotype of human P2Y<SB>12</SB>receptor gene is a homozygote of H1 haplotype, and the genotype of the 152539314th position of the genomic base sequence of the gene is represented by C/C, (the position is defined as the position of the genomic base sequence described in Gen Bank accession number NC_000003.9, but the position corresponds to the 152377525th position of the genomic base sequence described in Gen Bank accession number NC_000003.8), and the invention relates to the method for detecting a gene having possibility of causing coronary artery disease, the method for judging morbid risk thereof by using the method, a method for identifying a compound inducing desensitization on thrombocyte and a polynucleotide and reagents kit to be used in the method for the diagnosis. <P>COPYRIGHT: (C)2007,JPO&INPIT |
