发明名称 P38 INHIBITORS FOR THE TREATMENT AND PROPHYLAXIS OF LIVER CANCER
摘要 The present invention provides p38 inhibitors which are useful for the treatment and/or prophylaxis of liver cancer. In particular, the present invention provides compounds capable of inhibiting the intracellular expression of the p38 gamma protein in the hepatocytes of a subject relative to that observed in the absence of the compound, for use in the therapeutic treatment of liver cancer.
申请公布号 WO2016198698(A2) 申请公布日期 2016.12.15
申请号 WO2016EP63532 申请日期 2016.06.13
申请人 CNIC FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS 发明人 SABIO BUZO, Guadalupe;TOMÁS LOBA, Antonia;MARTÍNEZ GIL, Ana;GIL AYUSO-GONTAN, Carmen;GONZÁLEZ TERÁN, Bárbara;MANIERI, Elisa
分类号 A61K31/5377;A61P35/00;C07D231/40 主分类号 A61K31/5377
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