| 发明名称 |
METHOD FOR PRODUCING INDUCED PLURIPOTENT CELLS |
| 摘要 |
The invention relates to a method for producing induced pluripotent stem cells (iPS) by culturing somatic cells subjected to a cellular reprogramming method, characterised in that the somatic cells are cultured in the presence of netrin-1 or an analogue of netrin-1 at least at the beginning of the cellular reprogramming method. |
| 申请公布号 |
US2016369242(A1) |
申请公布日期 |
2016.12.22 |
| 申请号 |
US201515110979 |
申请日期 |
2015.01.13 |
| 申请人 |
CENTRE LEON BERARD ;UNIVERSITE CLAUDE BERNARD LYON 1 |
发明人 |
LAVIAL Fabrice;MEHLEN Patrick;BERNET Agnès |
| 分类号 |
C12N5/074 |
主分类号 |
C12N5/074 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for producing induced pluripotent stem cells (iPSCs) via culture of somatic cells subjected to a cell reprogramming process, comprising the step of culturing, the somatic cells in the presence of Netrin-1 or an analogue of Netrin-1 at least at the start of the cell reprogramming process, said analogue of Netrin-1 being capable of mimicking the biological activity of Netrin-1. |
| 地址 |
LYON FR |
