SYSTEM AND METHOD FOR THREE-DIMENSIONAL QUANTITATIVE EVALUAITON OF UTERINE FIBROIDS

摘要

A system (100) and method which assess the results of uterine fibroid embolization. A fibroid lesion is three-dimensionally segmented by a segmentation module (110) on contrast-enhanced arterial phase MRI or CBCT images and a differentiation process performed by a subtraction module (114) identifies actual contrast enhancement from background enhancement. The three-dimensional segmentation mask is then applied to the differentiated image and a region of interest is defined by a comparison module (116) in order to define a normalized threshold. A computation module (112) performs a voxel-by-voxel analysis of enhancing fibroid volume and quantifies the viable enhanced fibroid volume and overall fibroid volume in absolute numerical figures.

主权项

1. A system for three-dimensional quantitative evaluation, comprising:
a segmentation module configured to perform a three-dimensional segmentation on a contrast-enhanced imaging of a target and to compute the total volume based on the three-dimensional segmentation; a subtraction module configured to differentiate actual contrast enhancements from background enhancements on the contrast-enhanced imaging and to apply a three-dimensional segmentation mask obtained from the three-dimensional segmentation on the differentiated actual contrast enhancements; a comparison module configured to define a non-enhanced target portion as a region of interest and to compute contrast statistics for the region of interest in order to determine a normalized threshold value for target enhancement; and a computation module configured to define the enhanced target as voxels within the three-dimensional mask based on the threshold value and quantify the volume of the enhanced target.