发明名称 |
Bispecific CD33 and CD3 Binding Proteins |
摘要 |
Described herein are binding proteins that specifically bind to human CD33, and in particular to bispecific binding proteins that specifically bind to human CD33 and human CD3. Also described herein are bispecific tandem diabodies that bind to CD33 and CD33, and their uses for immunotherapy of CD33+ cancers, diseases and conditions such as acute myeloid leukemia (AML). |
申请公布号 |
US2016194409(A1) |
申请公布日期 |
2016.07.07 |
申请号 |
US201514937494 |
申请日期 |
2015.11.10 |
申请人 |
Amphivena Therapeutics, Inc. |
发明人 |
ELLWANGER Kristina;EVNIN Luke;FOX Judith A.;FUCEK Ivica;GUENOT Jeanmarie;KNACKMUSS Stefan;KUNKEL Lori;LITTLE Melvyn;MOLKENTHIN Vera;RAJKOVIC Erich;REUSCH Uwe;WALL Claudia;WEICHEL Michael;ZHUKOVSKY Eugene |
分类号 |
C07K16/46;A61K45/06;A61K39/395;C07K16/28 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
San Francisco CA US |