FLUORESCENCE BIOPSY SPECIMEN IMAGER AND METHODS

摘要

An imaging device is described that uses multiple cameras to image a biological sample on a turntable bathed in white light or fluorescing due to a systemically administered dye. Fluorescence farther away from an excitation light source can be compensated upon determining a 3-D position of portions of the sample. The turntable is turned and tilted in order to take enough images to prepare an animation of the sample. In a graphical user interface, the animation can be stopped, zoomed, and tilted per a user's gesture, touch, tablet-tilting, or other commands. The image manipulation can be with touch gestures entered using a sterilizable or disposable touch pen.

主权项

1. An apparatus for imaging a biological sample with fluorescence, the apparatus comprising:
a rotatable imaging stage adapted for supporting at least a portion of a biological sample within an imaging volume; a first camera; a monochromatic second camera; a switchable mounting system configured to alternatingly position a focal depth of the first camera and a focal depth of the second camera at a position in space; and an optical system configured to present an image of the at least a portion of the biological sample to the position in space.