| 发明名称 |
MARKERS FOR DIFFERENTIATION OF STEM CELLS INTO DIFFERENTIATED CELL POPULATIONS |
| 摘要 |
Provided herein are systems and methods for identifying cell-specific differentiation markers. In particular, provided herein are systems and methods for generating induced pluripotent cells (IPS) from human cells, differentiating the IPS into differentiated cells, and identifying differentiation specific markers. |
| 申请公布号 |
US2016230225(A1) |
申请公布日期 |
2016.08.11 |
| 申请号 |
US201615004188 |
申请日期 |
2016.01.22 |
| 申请人 |
REGENERATIVE MEDICAL SOLUTIONS, INC. |
发明人 |
XU XIAOFANG;ODORICO JON;FORSBERG ERIK;MAEL AMBER A.;TAGLIAVIA GUY |
| 分类号 |
C12Q1/68;A61K35/39;C12N5/071 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of identifying differentiation markers, comprising:
a) culturing a primary cell under conditions such that said primary cell de-differentiates to generate an induced pluripotent stem cell (iPSC); b) treating said iPSC under conditions such that said iPSC differentiates into a differentiated cell; and c) identifying molecular markers that are indicative of differentiation into said differentiated cell. |
| 地址 |
CHICAGO IL US |
