发明名称 |
COMPOUNDS AND METHODS FOR INHIBITING CANCER METASTASIS |
摘要 |
Agents for inhibiting cancer metastasis are provided. The methods comprise administering to a patient an antimetastatic agent that comprises one or more of: (a) a peptide sequence that is at least 50% identical to an OB-cadherin CAR sequence; (b) a non-peptide mimetic of an OB-cadherin CAR sequence; (c) a substance, such as an antibody or antigen-binding fragment thereof, that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding a polypeptide that comprises an OB-cadherin CAR sequence or analogue thereof.
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申请公布号 |
US2002169106(A1) |
申请公布日期 |
2002.11.14 |
申请号 |
US19990264516 |
申请日期 |
1999.03.08 |
申请人 |
BLASCHUK OREST W.;BYERS STEPHEN;GOUR BARBARA J.;SYMONDS JAMES MATTHEW |
发明人 |
BLASCHUK OREST W.;BYERS STEPHEN;GOUR BARBARA J.;SYMONDS JAMES MATTHEW |
分类号 |
G01N33/574;A61K38/00;C07K14/705;C07K14/78;C07K16/18;C12N15/09;C12P21/08;C12Q1/02;C12Q1/68;G01N33/68;(IPC1-7):A01N37/18;G01N33/48 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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