| 发明名称 |
Methods and Compositions for Inhibiting C-MET Dimerization and Activation |
| 摘要 |
The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.
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| 申请公布号 |
US2007098707(A1) |
申请公布日期 |
2007.05.03 |
| 申请号 |
US20060537751 |
申请日期 |
2006.10.02 |
| 申请人 |
GENENTECH, INC. |
发明人 |
KONG-BELTRAN MONICA;WICKRAMASINGHE DINELI M. |
| 分类号 |
A61K38/54;A61K38/00;A61K38/03;A61K38/08;A61K38/17;A61K38/18;C07H21/04;C07K14/475;C07K16/18;C07K16/22;C07K16/32;C12N9/99;G01N33/68 |
主分类号 |
A61K38/54 |
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