AMPHIPHILIC MACROCYCLIC DERIVATIVES AND THEIR ANALOGUES

摘要

Soluble amphiphilic macrocycle analogues having lipophilic groups attached t o one side of the units making up the macrocycle and hydrophilic groups attach ed to the other side. These amphiphilic macrocyclic derivatives have the abilit y to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilisation and/or stabilisation of various compounds. Embodiments of the present invention utilise macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.