发明名称 Derivatives of Variolin B
摘要 The invention provides antitumour compounds of formula (I), wherein R<SUP>1 </SUP>is an aromatic substituent; R<SUP>2 </SUP>is hydrogen or a substituent when the dotted line is absent, or R<SUP>2 </SUP>is absent when the dotted line represents a bond to give a double bond between the nitrogen which bears R<SUP>2 </SUP>and the carbon which bears R<SUP>3</SUP>; R<SUP>3 </SUP>is an oxo group =0 when the dotted line is absent or is a substituent when the dotted line represents a bond to give a double bond between the nitrogen bearing R<SUP>2 </SUP>and the carbon bearing R<SUP>3</SUP>; R<SUP>4 </SUP>is hydrogen or a substituent; and pharmaceutically acceptable salts thereof.
申请公布号 US2008033001(A1) 申请公布日期 2008.02.07
申请号 US20070829379 申请日期 2007.07.27
申请人 UNIVERSIDAD DE BARCELONA 发明人 ALVAREZ MERCEDES;PUENTES JOSE L.F.;BLEDA DAVID F.
分类号 A61K31/505;A61K31/519;A61K45/00;A61P35/00;C07D471/14 主分类号 A61K31/505
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