发明名称 |
HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTINS AND CXCR4 CHEMOKINE RECEPTORS |
摘要 |
Compounds, compositions, and methods for treatment and/or prevention of cancer and inflammatory diseases, and for releasing cells such as stem cells (e.g., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells in the blood are disclosed. For example, heterobifunctional compounds that inhibit both E-selectins and CXCR4 chemokine receptors are described and pharmaceutical compositions comprising at least one of the same. |
申请公布号 |
WO2016089872(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
WO2015US63191 |
申请日期 |
2015.12.01 |
申请人 |
GLYCOMIMETICS, INC. |
发明人 |
MAGNANI, JOHN, L.;SARKAR, ARUN, K.;PETERSON, JOHN, M. |
分类号 |
C07H15/207;A61K31/7034 |
主分类号 |
C07H15/207 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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