| 摘要 |
The present invention relates to a method for the rapid evaluation of bacterial susceptibility or non-susceptibility of bacteria to antibiotics that inhibit protein synthesis. The rationale is to identify bacterial responses that depend or are influenced by protein synthesis. If this response is prevented or reduced by the antibiotic that inhibits the protein synthesis, the bacteria are susceptible to this antibiotic. Otherwise, if the response keeps similar despite the incubation with the antibiotic, the bacteria are no susceptible or resistant to this antibiotic. These responses could be determined at the DNA level, cell wall level, morphological level or any other experimental approach, including metabolic, biochemical, physiological or genetic processes. |
