发明名称 |
Dual-Transfected Cells Lines As In Vitro Screening Tools For Pharmaceutical Compound Profiling: A Model For The Heptobiliary Elimination |
摘要 |
The invention is referring to several dual-transfected cell lines expressing human NTCP (Na/taurocholate Cotransporting Protein; SLC10A1) together with human BSEP (Bile Salt Export Pump; ABCB11) or human MRP2 (Multidrug Resistance Protein; ABCC2) suitable as an in vitro tool for pharmaceutical compound profiling particularly as a model for hepatobiliary elimination.
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申请公布号 |
US2007287167(A1) |
申请公布日期 |
2007.12.13 |
申请号 |
US20050594419 |
申请日期 |
2005.04.08 |
申请人 |
THEIS STEFAN;EISENBLAETTER TANJA |
发明人 |
THEIS STEFAN;EISENBLAETTER TANJA |
分类号 |
C12N5/06;C07K14/435;C07K14/47;C07K14/705;C12M1/22;C12N5/00;C12N5/02;C12N15/87;C12Q1/02;G01N33/50;G01N33/68 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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