Method of producing adipocytes from fibroblast cells

摘要

The present invention provides a method of producing progenitor cells, such as cells capable of being differentiated into a plurality of different cell types, from differentiated cells. Methods of using progenitor cells in differentiation and/or tissue or organ repair and/or regeneration and/or building are also provides. Methods of using progenitor cells in treatment and prophylaxis of conditions alleviated by administering stem cells or tissue or organ derived from stem cells to a subject or by grafting stem cells or tissue or organ derived from stem cells into a subject or by transplanting stem cells or tissue or organ derived from stem cells into a subject are also provided. Also included are progenitor cells and differentiated cells and/or tissues and/or organs derived therefrom, and kits comprising same.

主权项

1. A method for producing an adipocyte, said method comprising
incubating a fibroblast cell in a low-serum medium comprising a low serum concentration and without supplementation of any factors normally present in serum, and detaching the fibroblast cell, incubating the detached fibroblast for a time and under conditions sufficient to produce an adipocyte.