发明名称 FORMULATION OF OLOPATADINE
摘要 Stable formulations of Olopatadine, methods of making such formulations and methods of treatment using such formulations are provided.
申请公布号 US2016271097(A1) 申请公布日期 2016.09.22
申请号 US201415033171 申请日期 2014.08.27
申请人 NEPHRON PHARMACEUTICALS CORPORATION 发明人 Primelles-Perez Eric;Sims Jessica R.
分类号 A61K31/335 主分类号 A61K31/335
代理机构 代理人
主权项 1. A pharmaceutical composition comprising an aqueous solution of 11-(3 dimethylaminopropylidene)-6,11-dihydrodibenz(b,e) oxepin-2-acetic acid or a pharmaceutically acceptable salt thereof, and polyvinyl alcohol at a concentration of greater than 0.50% w/w and less than 1.75% w/w, wherein the pH is between 5.0 and 8.0, and the osmolality is between 260 and 340 mOsm/kg.
地址 Orlando FL US