发明名称 |
TOLERIZING TREATMENTS FOR AUTOIMMUNE DISEASE |
摘要 |
The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis. |
申请公布号 |
EP2988774(A4) |
申请公布日期 |
2016.11.02 |
申请号 |
EP20140788364 |
申请日期 |
2014.04.22 |
申请人 |
ENZO BIOCHEM, INC. |
发明人 |
NUSSENBLATT, ROBERT;LIU, BAOYING;WEI, LAI;RABBANI, ELAZAR;DONEGAN, JAMES, J. |
分类号 |
A61K39/00;A61K35/17;A61K39/38;A61P43/00;C40B30/04;G01N33/50 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|