发明名称 |
ABUSE-RESISTANT PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF OPIOID DEPENDENCE |
摘要 |
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof, in associative admixture with particles comprising a weak acid, or particles comprising weakly-acidic buffer forming materials. The composition may further comprise a disintegrant and/or particles of a pharmacologically-effective amount of naloxone, or a pharmaceutically-acceptable salt thereof. The compositions are useful in the treatment of opioid dependency/addiction and/or pain. |
申请公布号 |
US2016375010(A1) |
申请公布日期 |
2016.12.29 |
申请号 |
US201615261571 |
申请日期 |
2016.09.09 |
申请人 |
Orexo AB |
发明人 |
Fischer Andreas |
分类号 |
A61K31/485;A61K9/00;A61K9/20 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical composition comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof, in associative admixture with particles comprising a weak acid, or particles comprising weakly-acidic buffer forming materials. |
地址 |
Uppsala SE |