发明名称 |
Cyclocarbamate derivatives as progesterone receptor modulators |
摘要 |
This invention provides compounds of Formula (I): wherein R<1 >and R<2 >are independent substituents or are fused to form spirocyclic rings; R<3 >R<C >and R<4 >are as defined herein; and R<5 >is a substituted benzene ring or a substituted five or six membered heterocyclic ring having in its backbone 1, 2, or 3 heteroatoms including O, S, SO, SO2 or NR<6>; or pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions and methods using the compounds as antagonists of the progesterone receptor.
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申请公布号 |
US2004186101(A1) |
申请公布日期 |
2004.09.23 |
申请号 |
US20040767813 |
申请日期 |
2004.01.29 |
申请人 |
WYETH;LIGAND PHARMACEUTICALS, INC. |
发明人 |
ZHANG PUWEN;TEREFENKO EUGENE A.;FENSOME ANDREW;WROBEL JAY E.;FLETCHER HORACE;ZHI LIN;JONES TODD K.;EDWARDS JAMES P.;TEGLEY CHRISTOPHER M. |
分类号 |
C07D265/12;A61K31/536;A61K31/537;A61P15/00;A61P15/18;A61P35/00;A61P43/00;C07D265/18;C07D413/04;C07D413/10;C07D417/04;C07F9/6533;(IPC1-7):A61K31/535 |
主分类号 |
C07D265/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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