发明名称 NOVEL DIAZABICYCLO[2.2.2]OCTANE DERIVATIVE
摘要 Provided are: a compound having an antagonistic activity on an orexin receptor, a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt; a pharmaceutical composition characterized by containing the compound, the pharmaceutically acceptable salt or the solvate as an active ingredient; and a use of the compound or the pharmaceutical composition for medical purposes, specifically a use of the compound or the pharmaceutical composition as a prophylactic and/or therapeutic agent for diseases associated with an orexin receptor, such as sleep disorders, mental diseases, neurodegenerative diseases, memory impairments and eating disorders, particularly insomnia (an insomniac symptom) which is one of sleep disorders. Specifically provided is a compound represented by formula (I), a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt.
申请公布号 WO2016088813(A1) 申请公布日期 2016.06.09
申请号 WO2015JP83926 申请日期 2015.12.02
申请人 MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 HOTTA DAIDO;SAKURADA ISAO
分类号 C07D471/08;A61K31/4995;A61K31/506;A61K45/00;A61P25/20;A61P43/00 主分类号 C07D471/08
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