发明名称 System and Method for Controlling Neural and Muscular Function
摘要 A system and method for controlling neural and muscular function is disclosed in which opsins are introduced into a neural circuit such that the control of optical signals transmitted to the opsins results in the control of neural and muscular functions. Specifically disclosed is the control of the bladder, bowel, and sexual functions of a human.
申请公布号 US2016250495(A1) 申请公布日期 2016.09.01
申请号 US201615149261 申请日期 2016.05.09
申请人 Creasey Graham 发明人 Creasey Graham
分类号 A61N5/06;A61M5/00 主分类号 A61N5/06
代理机构 代理人
主权项 1. A method for controlling bladder, bowel, or sexual dysfunction comprising: preparing first and second sets of opsin sites by introducing first and second pluralities of opsins responsive to first and second light profiles, at first and second opsin sites located on first and second neurons, via at least one of either synaptic or retrograde transfer of viral vectors from first and second introduction targets, respectively, the introduction targets including one or more of a patient's bladder wall, external urethral sphincter, internal urethral sphincter, bowel wall, external anal sphincter, internal anal sphincter, sacral afferent nerves, sacral efferent nerves, pudendal motor nerves, pudendal sensory nerves, pelvic parasympathetic nerves, and pelvic sympathetic nerves; optically connecting one or more light sources to the first and second sets of opsin sites, the one or more light sources producing one or more optical signals to the first and second sets of opsin sites; communicatively connecting one or more microprocessors to the one or more light sources to control the one or more light sources to produce the one or more optical signals; and communicatively connecting a sensor to the one or more microprocessors, for transmitting a signal to at least one of the one or more microprocessors to control the one or more light sources.
地址 Menlo Park CA US