发明名称 |
SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS |
摘要 |
Compositions and methods are described herein for chemically inducing cells to change their differentiation state and become neuronal cells. |
申请公布号 |
US2016250260(A1) |
申请公布日期 |
2016.09.01 |
申请号 |
US201414913549 |
申请日期 |
2014.08.26 |
申请人 |
The J. David Gladstone Ins., a testamentary trust established under the Will of J. David Gladstone |
发明人 |
Lin Changsheng;Ding Sheng |
分类号 |
A61K35/30;A61K31/4015;A61K31/352;C12N5/0793;A61K31/506;A61K31/4439;A61K31/222;A61K31/4402;A61K45/06;A61K31/196 |
主分类号 |
A61K35/30 |
代理机构 |
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代理人 |
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主权项 |
1. A composition comprising the following agents: a GSK3 inhibitor, an ALK4/5/7 inhibitor, an HDAC inhibitor, and a p300 activator. |
地址 |
San Francisco CA US |