发明名称 |
INJECTIBLE AGENT AND DEPOT FORMATION METHOD |
摘要 |
The purpose of the present invention is to provide a novel injectable agent having an excellent medicinal agent sustained release property. The injectable agent according to the present invention comprises a medicinal agent, trehalose and gellan gum. It is preferred that the contents of the medicinal agent, trehalose and gellan gum are 0.0001 to 50.00% (w/v), 0.1 to 50.0% (w/v) and 0.01 to 3.00% (w/v), respectively, relative to the total volume of the injectable agent. It is also preferred that the injectable agent can form a depot upon exposure to a phosphate buffer solution or a body fluid (tear fluid, vitreous fluid, etc.). |
申请公布号 |
US2016303240(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
US201615190855 |
申请日期 |
2016.06.23 |
申请人 |
Santen Pharmaceutical Co., Ltd. |
发明人 |
OKI Kenji;YAMADA Kazuhito;MIYAZAKI Tatsuya;OKABE Komei;HABASHITA Sayo;ENOMOTO Hiroshi;YOSHII Kenta |
分类号 |
A61K47/26;A61K47/36;A61K47/02;A61K31/444;C07K16/00;A61K31/573;A61K31/196;A61K31/405;A61K31/542;A61K31/55;A61K9/00;A61K31/436 |
主分类号 |
A61K47/26 |
代理机构 |
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代理人 |
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主权项 |
1. An injectable agent comprising a medicinal agent, trehalose and gellan gum. |
地址 |
Osaka JP |