| 发明名称 |
DNA VACCINE CONTAINING SPECIFIC EPITOPE OF APOLIPOPROTEIN (a) |
| 摘要 |
The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide. |
| 申请公布号 |
US2016303211(A1) |
申请公布日期 |
2016.10.20 |
| 申请号 |
US201615201029 |
申请日期 |
2016.07.01 |
| 申请人 |
AnGesMG, Inc. |
发明人 |
KYUTOKU Mariko;NAKAGAMI Hironori;KORIYAMA Hiroshi;NAKAGAMI Futoshi;MORISHITA Ryuichi |
| 分类号 |
A61K39/00;C12N7/00;A61K39/29 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for treating or preventing a lipoprotein(a)-related disease in a mammal, comprising administering effective amount of an expression vector encoding an antigen polypeptide inserted with an amino acid sequence comprising a specific epitope of apolipoprotein (a) in the mammal. |
| 地址 |
Osaka JP |
