IMPLANTABLE THERAPEUTIC DEVICES

摘要

Described are implantable devices (105) and therapeutic agent delivery formulations for the sustained release of therapeutic agents. In one aspect, described is a device to treat an ocular condition of an eye. The device has a proximal region. A tubular body (115) is coupled to the proximal region and has an outer diameter configured to be inserted at least in part into the eye. A reservoir (130) is in fluid communication with the tubular body and has a volume sized to receive an amount of a formulation of a therapeutic agent. One or more outlets (135) are in fluid communication with the reservoir and configured to release therapeutic amounts of the therapeutic agent into the eye for an extended time when the one or more outlets are positioned inside the eye.

主权项

1. A device to treat an ocular condition of an eye, the device comprising:
a proximal region; a tubular body coupled to the proximal region having an outer diameter configured to be inserted at least in part into the eye; a reservoir in fluid communication with the tubular body and having a volume sized to receive an amount of a formulation of a therapeutic agent; and one or more outlets in fluid communication with the reservoir and configured to release therapeutic amounts of the therapeutic agent into the eye for an extended time when the one or more outlets are positioned inside the eye.