NITROGENOUS CONDENSED-RING COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR

摘要

A nitrogenous condensed-ring compound of the general formula: [I] (wherein the symbols are as defined in the description), or pharmaceutically acceptable salt thereof; and an anti-HIV agent comprising any of the compounds. These compounds are effective in the inhibition of HIV integrase activity and are useful as an anti-HIV agent and as a curative or preventive agent for AIDS. More effective anti-HIV agent can be obtained by the use thereof in combination with another anti-HIV agent, such as a protease inhibitor or a reverse transcriptase inhibitor. Exhibiting of high inhibiting activity specific to integrase would ensure use thereof as a medical agent that is safe to human body and can reduce side effects thereon.