A biomolecular field-effect transistor comprising a polypeptide film and a method for the manufacture thereof

摘要

An organic field-effect transistor (T) is described, which comprises: a pair of source and drain electrode (S, D) which are formed on an electrically insulating layer (INS) and which are adapted to operate as the source and the collector of a flow of electric charge-carriers in which the majority carriers are free holes, and a layer of organic conductive material (F) which is disposed between the electrodes (S, D) for the formation of a conduction region through which the flow of charge carriers passes and the resistance of which is modulated by the application of a control voltage to a gate electrode (G) insulated from the conduction region, characterized in that the layer of organic conductive material (F) is a layer of biomolecular conductive material including a film of polypeptides or oligopeptides (P) . The method for the manufacture of a transistor of this type comprises the formation of a film (F) of polypeptides or oligopeptides (P) on the electrically insulating layer (INS) in contact with the source and drain- electrodes (S, D) by immobilization of the polypeptides/oligopeptides (P) on the layer (INS) by deposition of a buffer solution of polypeptides/oligopeptides (P) , subsequent incubation for a predetermined period of time and at a predetermined temperature, removal of the buffer solution, and drying by exposure to a stream of gas.