| 发明名称 |
CYCLOPROPYL-PIPERAZINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS |
| 摘要 |
<p>Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type calcium channel activity are disclosed. Specifically, a series of compounds containing both a piperazine ring and a cyclopropyl ring are disclosed of the general formula (I) where X<SUP>1</SUP> and X<SUP>2</SUP> are linkers.</p> |
| 申请公布号 |
WO2008043183(A1) |
申请公布日期 |
2008.04.17 |
| 申请号 |
WO2007CA01827 |
申请日期 |
2007.10.12 |
| 申请人 |
NEUROMED PHARMACEUTICALS LTD.;PAJOUHESH, HASSAN;PAJOUHESH, HOSSEIN;KAUL, RAMESH |
发明人 |
PAJOUHESH, HASSAN;PAJOUHESH, HOSSEIN;KAUL, RAMESH |
| 分类号 |
C07D295/182;A61K31/495;A61K31/496;A61K31/5377;C07D401/08;C07D403/08;C07D403/12;C07D413/08;C07D413/14 |
主分类号 |
C07D295/182 |
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