发明名称 |
MUTANT PROTEIN OF GLYCOSYLTRANSFERASE AND USES THEREOF |
摘要 |
Provided are a mutant protein of glycosyltransferase and uses thereof. Specifically, by using homology alignment and site-directed mutagenesis, a new mutant protein of glycosyltransferase is discovered. The mutant protein is a non-natural protein with glycosyltransferase catalytic activity, which contains the following core amino acids related to enzyme catalytic activity: the amino acid at position 142 is A, the amino acid at position 144 is H or F and the amino acid at position 339is G, wherein the number of the amino acid position is based on the sequence shown in SEQ ID NO: 13. |
申请公布号 |
WO2016119756(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016CN73074 |
申请日期 |
2016.02.01 |
申请人 |
SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES |
发明人 |
ZHOU, ZHIHUA;WEI, WEI;YAN, XING;WANG, PINGPING;WEI, YONGJUN;YANG, CHENGSHUAI |
分类号 |
C12N9/10;A01H5/00;C12N1/21;C12N5/10;C12N15/54;C12N15/70;C12N15/82;C12P33/20 |
主分类号 |
C12N9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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