发明名称 COMPOSITIONS AND METHODS FOR CREATING PANCREATIC CANCER ANIMAL MODEL
摘要 Certain embodiments are directed kits comprising components for producing a mammalian cancer model. In certain aspects the components are expression vectors. In certain embodiments one or more expression vector is engineered to express a KrasG12D polypeptide, a p53 transcriptional suppressor, SMAD4 transcriptional suppressor, p16/CDKN2 A transcriptional suppressor. In certain aspects the transcriptional suppressor is a short hairpin RNA (shRNA) or other nucleic acid used for RNA interference.
申请公布号 WO2016115558(A3) 申请公布日期 2016.09.01
申请号 WO2016US13807 申请日期 2016.01.18
申请人 DOIRON, Bruno 发明人 DOIRON, Bruno
分类号 A01N63/00;A01K67/00;C07H21/04;C12N15/00;G01N33/00 主分类号 A01N63/00
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