发明名称 |
PROCESS FOR PRODUCTION OF CARBAPENEM DERIVATIVE AND CRYSTALLINE INTERMEDIATE THEREFOR |
摘要 |
<p>An object of the present invention is to provide a carbapenem synthetic intermediate which is advantageous in an industrial process. There are provided a process for producing Compound (I), or a pharmaceutically acceptable salt, or a solvate, or a crystal thereof, comprising reacting Compound (III) and Compound (IV) in the presence of the secondary amine, and a benzyl alcoholated crystal of Compound (I). There are further provided a method of deprotecting Compound (I) with a Pd catalyst, and a crystal of Compound (IV).</p> |
申请公布号 |
EP1852436(A4) |
申请公布日期 |
2010.02.24 |
申请号 |
EP20060713624 |
申请日期 |
2006.02.14 |
申请人 |
SHIONOGI CO., LTD. |
发明人 |
UENAKA, MASAAKI;HOZUMI, YASUYUKI;NOGUCHI, KOUICHI;KOMURASAKI, TADAFUMI |
分类号 |
C07D477/00;A61K31/40;A61P31/00 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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