发明名称 |
Anti-CD20 monoclonal antibody |
摘要 |
<p>Disclosed is a monoclonal antibody capable of inducing a specific biological reaction through the binding of the monoclonal antibody to a CD20 antigen on the surface of a cell. A monoclonal antibody having a high binding affinity to an extracellular epitope of a CD20 antigen and also having biological activities including a cell growth inhibitory activity is cloned. The monoclonal antibody is chimerized or humanized to develop a therapeutic agent for a disease in which B cells are involved.</p> |
申请公布号 |
EP2143795(A3) |
申请公布日期 |
2010.02.24 |
申请号 |
EP20090011119 |
申请日期 |
2006.03.31 |
申请人 |
BIOMEDICS INC. |
发明人 |
NUMAZAKI, MASANORI;NAKAMURA, TETSUO;USUDA, SADAKAZU;PADLAN, EDUARDO A. |
分类号 |
C12N15/09;A61K39/395;A61P7/00;A61P7/06;A61P19/02;A61P29/00;A61P35/00;A61P35/02;A61P37/02;C07K16/28;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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