Naloxol-polyethylene glycol conjugates of the formula:
are provided in oxalate or phoshate salt forms including crystalline forms. To achieve a central analgesic effect, the conjugates will be administered an opioid agonist.
申请公布号
HUE026726(T2)
申请公布日期
2016.07.28
申请号
HUE11829686
申请日期
2011.09.29
申请人
AstraZeneca AB;Nektar Therapeutics
发明人
ÃSLUND, Bengt Leonard;AURELL, Carl-Johan;BOHLIN, Martin Hans;SEBHATU, Tesfai;YMEN, Bo Ingvar;HEALY, Eric Thomas;JENSEN, David Richard;JONAITIS, David Thomas;PARENT, Stephan