| 发明名称 |
MULTIVALENT DENGUE VIRUS VACCINE |
| 摘要 |
The present invention provides vaccine compositions of attenuated dengue virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against all four dengue virus serotypes by administration of attenuated dengue-1, dengue-2, dengue-3, and dengue-4 virus.
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| 申请公布号 |
US2007087015(A1) |
申请公布日期 |
2007.04.19 |
| 申请号 |
US20030626315 |
申请日期 |
2003.07.24 |
| 申请人 |
ECKELS KENNETH I;PUTNAK JOSEPH R;DUBOIS DORIA R;INNIS BRUCE L;HOKE CHARLES H;SUN WELLINGTON;KANESA-THASAN NIRANJAN |
发明人 |
ECKELS KENNETH I.;PUTNAK JOSEPH R.;DUBOIS DORIA R.;INNIS BRUCE L.;HOKE CHARLES H.;SUN WELLINGTON;KANESA-THASAN NIRANJAN |
| 分类号 |
A61K39/395;A61K45/00;A61K39/12;A61P31/12;C12N7/08 |
主分类号 |
A61K39/395 |
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