The invention relates to thiadiazole compounds useful for treating diseases mediated by protein kinase B (PKB). The invention also relates to the therapeutic use of such thiadiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
申请公布号
ZA200703975(B)
申请公布日期
2009.01.28
申请号
ZA20070003975
申请日期
2007.05.16
申请人
AMGEN, INC.
发明人
ZENG, QINGPING;YAO, GUOMIN;WOHLHIETER, GEORGE ERICH;VISWANADHAN, VELLARKAD N.;TASKER, ANDREW;RIDER, JAMES THOMAS;MONENSCHEIN, HOLGER;DOMINGUEZ, CELIA;BOURBEAU, MATTHEW, PAUL