| 发明名称 |
METHODS OF INCORPORATION OF TRANSCRIPT CHROMOSOMAL LOCUS INFORMATION FOR IDENTIFICATION OF BIOMARKERS OF DISEASE RECURRENCE RISK |
| 摘要 |
The present invention provides methods for incorporating transcript chromosomal locus information for identification of biomarkers of disease recurrence risk. |
| 申请公布号 |
US2016259881(A1) |
申请公布日期 |
2016.09.08 |
| 申请号 |
US201415033055 |
申请日期 |
2014.10.28 |
| 申请人 |
GENOMIC HEALTH, INC. |
发明人 |
Kiefer Michael C.;Collin Francois;Levy Samuel;Baker Joffre B.;Crager Michael R.;Segal Mark R. |
| 分类号 |
G06F19/18;G06F19/26;C12Q1/68;G06F19/20 |
主分类号 |
G06F19/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for identifying a string of genes that are associated with clinical outcome of a disease, comprising
measuring gene expression levels of a plurality of genes obtained from a sample from a patient having the disease; normalizing the gene expression levels to obtain normalized gene expression levels; associating the normalized gene expression levels with the clinical outcome; identifying genes that significantly associate with the clinical outcome; aligning the genes that significantly associate with the clinical outcome to a human chromosome physical map; and identifying a string of genes that positively or negatively associate with the clinical outcome. |
| 地址 |
Redwood City CA US |
